Nuclear Magnetic Resonance Spectroscopy

Instrument: Bruker Avance III 500 equipped with CP-MAS H/X (solid probe)


Nuclear Magnetic Resonance (NMR) spectroscopy is an exquisitely sensitive method for analysing the local magnetic environments of atoms. Within molecules, every atom affects the magnet environment of other atoms, particularly when they are close together in space or physically bonded to each othetr.

By monitoring the magnetic environment of the atoms we can determine the structure. of molecules, either in isolation or when interacting with other molecules

Since every conceivable environmental condition has a cumulative effect on this magnetic environment - such as molecular interactions, temperature, pH, solution environment - NMR spectroscopy is a very versatile method of analysis.

NMR is typically used for structure determination of small molecules, such as cehmicals or small biomolecules. NMR can also by used to investigate mixtures of molecules and can even solve 3-dimensional structures of proteins.

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